Capsaicin

>98% (HPLC)

TRPV1 channels

Synthetic

Capsaicin (#C-125) is a highly pure, Synthetic, and biologically active compound.

305.4

Capsaicin is one of the most powerful chemical agonists of the TRPV1 (transient receptor potential vanilloid) channel. It is a small lipophilic molecule derived from hot chili peppers that acts on sensory neurons by opening TRPV1, a principal transduction channel for nociception1. Capsaicin acts directly on TRPV12, with half-maximal effective concentration of 711.9 nM in Xenopus oocytes3 and 0.29 μM in HEK293 cells4.

Ethanol. Centrifuge all product preparations before use (10000 x g 5 min).

0.1-10 μM.

Lyophilized

(E)-N-[(4-羟基-3-甲氧基苯基)甲基]-8-甲基-6-壬烯酰胺

(E)-Capsaicin, CPS

C18H27NO3.

404-86-4

Up to one week at 4°C or six months at -20°C.