6-Hydroxydopamine hydrobromide

6-Hydroxydopamine hydrobromide is a neurotoxin which destroys catecholaminergic terminals. 参考文献 He, Y., 6-Hydroxydopamine induced apoptosis of dopaminergic cells in the rat substantia nigra. Brain Res. 858, 163-166, (2000) Fink, D.W., et al., Differential effects of 6-hydroxydopamine-induced ablation of peripheral and central adrenergic axons on C-1300 murine neuroblastoma tumor growth and catecholamine concentration in the A/J mouse. J. Pharmacol. Exp. Ther. 262, 1070-1075, (1992) Super, H., Degeneration of Cajal-Retzius cells in the developing cerebral cortex of the mouse after ablation of meningeal cells by 6-hydroxydopamine. Brain Res. Brain Res. Rev. 98, 15-20, (1997) Soto-Otero, R., et al., Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease. J. Neurochem. 74, 1605-1612, (2000)

250.09

6-Hydroxydopamine hydrobromide is an oxygen compound that destroys catecholaminergic terminals

6-OHDA

C1=C(C(=CC(=C1O)O)O)CCN.Br

C8H11NO3 HBr

636-00-0