6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester

6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester is a photoactive, heterobifunctional cross-linking reagent incorporating an extended spacer. Ordinarily, the initial reaction couples via ester to primary amine by amide bond formation in the pH range of 6.5-8.5. The second bonding, non-specific and rapid, occurs during UV irradiation (250-350 nm) via reactive nitrene. 参考文献 Ballmer-Hofer, K., et al., Isolation of in situ crosslinked ligand-receptor complexes using an anticrosslinker specific antibody. Anal. Biochem. 126, 246-250, (1982)

390.35

干冰

6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester is a photoactive, heterobifunctional cross-linking reagent

C1CC(=O)N(C1=O)OC(=O)CCCCCNC2=C(C=C(C=C2)N=[N+]=N)[N+](=O)[O-]

C16H18N6O6

64309-05-3