品牌： CST
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对比
咨询分子量：
18
18
反应种属：
Human,Mouse,Rat,Monkey,
Human,Mouse,Rat,Monkey,
产品介绍
产品信息
抗原名称
alpha-Synuclein
来源纯化
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the carboxy-terminal sequence of human α-synuclein. Antibodies are purified by protein A and peptide affinity chromatography.
宿主
Rabbit
简单描述
Polyclonal Antibody for studying Synuclein-alpha. Cited in 91 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, α-Synuclein Antibody (CST #2642) is ready to ship.
商品描述
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
分子量
18
研究领域
神经科学
应用
反应种属
Human,Mouse,Rat,Monkey,
目标/特异性
Specificity/Sensitivity
α-Synuclein Antibody detects the alpha isoform of synuclein. The antibody may cross-react with β-synuclein.
Species Reactivity:
Human, Mouse, Rat, Monkey
敏感性
Endogenous
背景
背景
α-Synuclein 是一个含有 140 个氨基酸的蛋白，主要在脑中表达。α-Synuclein 也是致病性 Lewy 体和 Lewy 神经突的主要组分。研究表明 α-synuclein 基因突变与帕金森病有关 (1)。
Goldberg, M.S. and Lansbury Jr., P.T. (2000) Nat. Cell Biol. 2, 115-119.
研究领域
神经科学
翻译后修饰
Unmodified
制备和贮存
保存方式
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
数据库链接
Entrez-Gene ID
6622
UniProt ID
P37840
参考图片
Western blot analysis of extracts from 293, HeLa, rat brain and mouse brain cell extracts, using α-Synuclein Antibody.
Western blot分析293、Hela、大鼠大脑和小鼠大脑细胞提取物，使用的抗体是α-Synuclein Antibody 兔多抗。
Immunoprecipitation of α-synuclein from HeLa cell extracts, using α-Synuclein Antibody. Lane 1 is lysate control, lane 2 is antibody alone and lane 3 is both antibody and lysate.
使用α-Synuclein Antibody 兔多抗对Hela细胞提取物中的 α-synuclein蛋白进行免疫共沉淀实验。Lane 1是裂解液对照，Lane 2仅加入抗体，Lane 3是既有裂解液又有抗体。
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危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)