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产品介绍
产品信息
抗原名称
alpha-Synuclein
来源纯化
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human α-Synuclein protein.
宿主
Rabbit
简单描述
Monoclonal Antibody for studying Synuclein-alpha. Cited in 2 publications. Validated for WB, WB, IP, IHC, IF, IF. Available in 2 sizes. Highly specific and rigorously validated in-house, α-Synuclein (E4U2F) XP® Rabbit Monoclonal Antibody (CST #51510) is ready to ship.
商品描述
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Simple Western™ | 1:10 - 1:50 |
| Immunoprecipitation | 1:50 |
| Immunohistochemistry (Paraffin) | 1:100 - 1:400 |
| Immunofluorescence (Frozen) | 1:400 - 1:1600 |
| Immunofluorescence (Immunocytochemistry) | 1:400 - 1:1600 |
分子量
18
研究领域
神经科学
应用
反应种属
Human,Mouse,Rat,
目标/特异性
Specificity/Sensitivity
α-Synuclein (E4U2F) XP® Rabbit mAb recognizes endogenous levels of total α-Synuclein protein. This antibody does not cross-react with β-Synuclein. Weak nuclear staining of uncertain specificity was observed in limited ovarian tumors by immunohistochemistry.
Species Reactivity:
Human, Mouse, Rat
敏感性
Endogenous
背景
背景
α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease (1).
1.Goldberg, M.S. and Lansbury Jr., P.T. (2000) Nat. Cell Biol. 2, 115-119.
研究领域
神经科学
翻译后修饰
Unmodified
制备和贮存
保存方式
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. For a carrier-free (BSA and azide free) version of this product see product #45083.
数据库链接
Entrez-Gene ID
6622
UniProt ID
P37840
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危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)