品牌： Alomone
下载产品说明书
用小程序，查商品更便捷
收藏
对比
咨询纯度：
Affinity purified on immobilized antigen.
Affinity purified on immobilized antigen.
反应种属：
H, M, R
H, M, R
产品介绍
产品信息
纯化方式
Affinity purified on immobilized antigen.
宿主
Rabbit
简单描述
A Rabbit Polyclonal Antibody to KV10.1 Channel
商品描述
Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to KV10.1 Channel
同种型
Rabbit IgG.
纯度
Affinity purified on immobilized antigen.
组成成分
抗蛋白抗体
基因
KCNH1
应用
实验应用
ICC, IF, IHC, IP, WB
反应种属
H, M, R
目标/特异性
The antibody is specific for KV10.1 and will not cross-react with KV10.2.
背景
别名
KV10.1, Ether-a-go-go potassium channel 1, hEAG1
背景
KV10.1 is a member of the Ether-a-go-go family of voltage-activated K+ channels. To date, the family includes 8 members: the closely related KV10.2 (EAG-2) protein, the KV12 (elk) subfamily (elk1, elk2, elk3) and the KV11 (erg) proteins (erg1, erg2, erg3). As with the other KV superfamily members, KV10.1 shows the characteristic 6 transmembrane domains with intracelullar N and C termini.
The KV10 subfamily current is characterized by outward rectification without inactivation and slow activation kinetics. Its expression is normally confined to the brain where its physiological function has not yet been clarified.
Intriguingly, the KV10.1 channel has been implicated in malignant tumor development. It has been shown that KV10.1 was inappropriately expressed in several cancer cell lines. Moreover, one study showed that KV10.1 by itself had oncogenic potential, as a cell line transfected with the channel, induced aggressive and faster tumor growth in vivo as compared to a cell line transfected with an unrelated KV channel.
The KV10 subfamily current is characterized by outward rectification without inactivation and slow activation kinetics. Its expression is normally confined to the brain where its physiological function has not yet been clarified.
Intriguingly, the KV10.1 channel has been implicated in malignant tumor development. It has been shown that KV10.1 was inappropriately expressed in several cancer cell lines. Moreover, one study showed that KV10.1 by itself had oncogenic potential, as a cell line transfected with the channel, induced aggressive and faster tumor growth in vivo as compared to a cell line transfected with an unrelated KV channel.
制备和贮存
溶解方法
25 μl, 50 μl or 0.2 ml double distilled water (DDW), depending on the sample size.
保存方式
The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
数据库链接
Entrez-Gene ID
65198
UniProt ID
Q63472
声明 ：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。
危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)