

品牌: Alomone








纯度:
Affinity purified on immobilized peptide.
Affinity purified on immobilized peptide.
反应种属:
H, R
H, R
产品介绍
产品信息
纯化方式
Affinity purified on immobilized antigen.

宿主
Rabbit

免疫原
Peptide (C)EDPKGSDSENSVTKNPLRK, corresponding to amino acid residues 842-860 of rat KCNH5 (Accession Q9EPI9). Intracellular, C-terminus.

简单描述
A Rabbit Polyclonal Antibody to KV10.2 Channel

商品描述
Alomone Labs is pleased to offer a highly specific antibody directed against an intracellular epitope of the rat KV10.2 channel. Anti-KCNH5 (EAG-2) Antibody (#APC-053) can be used for western blot and immunohistochemistry applications. It has been designed to recognize KV10.2 from rat and human samples. The antibody is specific for KV10.2 and will not cross-react with KV10.1.

同种型
Rabbit IgG.

纯度
Affinity purified on immobilized peptide.

形式
Lyophilized

组成成分
抗钾电压门控通道亚家族H成员5抗体,0.05%叠氮化钠溶液

基因
KCNH5

应用
实验应用
IF, IHC, WB

反应种属
H, R

目标/特异性
The antibody is specific for KV10.2 and will not cross-react with KV10.1.

背景
别名
KV10.2, Ether-a-go-go potassium channel 2, hEAG2

背景
KV10.2 is a member of the Ether-a-go-go family of voltage-activated potassium channels. The family includes today 8 members: the closely related KV10.1 protein, the KV12 (elk) (elk1, elk2, elk3) and the KV11 (erg) proteins (erg1, erg2, erg3).
The eag subfamily current is characterized by outward rectification without inactivation and slow activation kinetics. No specific pharmacological blocker has been described.
Tissue distribution of KV10.2 expression in rats is restricted to neuronal tissue with greater expression in the cortex and thalamus. In humans, KV10.2 mRNA was detected in heart and skeletal muscle in addition to brain.
The physiological role of KV10.2 is unknown at the moment.
The eag subfamily current is characterized by outward rectification without inactivation and slow activation kinetics. No specific pharmacological blocker has been described.
Tissue distribution of KV10.2 expression in rats is restricted to neuronal tissue with greater expression in the cortex and thalamus. In humans, KV10.2 mRNA was detected in heart and skeletal muscle in addition to brain.
The physiological role of KV10.2 is unknown at the moment.

制备和贮存
溶解方法
50 μl or 0.2 ml double distilled water (DDW), depending on the sample size.

保存方式
The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
数据库链接
Entrez-Gene ID
171146

UniProt ID
Q9EPI9

研究资源识别码
AB_2039935.

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