首页
Anti-NaV1.6 (SCN8A) Antibody
Anti-NaV1.6 (SCN8A) Antibody

Anti-NaV1.6 (SCN8A) Antibody

分享
品牌： Alomone
用小程序，查商品更便捷
收藏
对比对比
咨询咨询
    纯度：
    Affinity purified on immobilized antigen.
    Affinity purified on immobilized antigen.
    反应种属：
    H, M, R
    H, M, R
    展开
    产品介绍
    产品信息
    宿主
    兔
    商品描述
    Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to NaV1.6 Channel
    同种型
    Rabbit IgG.
    纯度
    Affinity purified on immobilized antigen.
    组成成分
    电压门控钠离子通道蛋白抗体(多克隆抗体);磷酸盐缓冲液;防腐剂(0.05%叠氮化钠溶液)
    应用
    实验应用
    IC, IH, WB
    反应种属
    H, M, R
    背景
    别名
    SCN8A,
    背景
    Voltage-gated sodium channels (NaV) are essential for the generation of action potentials and for cell excitability.1 NaV channels are activated in response to depolarization and selectively allow flow of Na+ ions. To date, nine NaV α subunits have been cloned and named NaV1.1-NaV1.9.4-5  The NaV channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive (NaV1.1, NaV1.2, NaV1.3, NaV1.4, NaV1.6 and NaV1.7)  and TTX-resistant (NaV1.5, NaV1.8 and NaV1.9).2-3 Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. Expression of the α subunit isoform is developmentally regulated and tissue specific. Sodium channels in the adult central nervous system and heart contain β1 through β4 subunits, whereas sodium channels in adult skeletal muscle have only the β1 subunit.6,7
     
    NaV1.6 is highly expressed in adult brain and localized at high density in nodes of Ranvier and axon initial segments and at lower density in dendrites and cell bodies of some neurons. NaV1.6 channels are also expressed at high levels in cerebellar Purkinje neurons.8-11
    声明 ：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。
    货号：
    ASC-009-0.2ml
    一键复制
    询价
    0.2ml
    25ul
    50ul
    Alomone奖励计划
    详情
    选择数量
    当前规格1件起购 
    配送至
    预计2-3周送达，快递: 免运费，若需干冰额外收费
    询价 大包装询价