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Anti-P2Y12 Receptor Antibody

品牌： Alomone

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参数

纯度：

Affinity purified on immobilized antigen.

反应种属：

H, M, R

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产品介绍

产品信息

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简单描述

A Rabbit Polyclonal Antibody to P2Y12 Receptor

商品描述

Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to P2Y12 Receptor

纯度

Affinity purified on immobilized antigen.

组成成分

嘌呤受体多克隆抗体，0.05%叠氮化钠溶液，磷酸盐缓冲液

应用

实验应用

IC, IFC, IH, WB

反应种属

H, M, R

背景

The P2Y receptors belong to the G-protein coupled receptors superfamily.

They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP AND UDPA. Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.^1-3

The P2Y12 receptor is co-expressed with P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular Ca²⁺ upon activation.

The only other expression of P2Y12 was found in brain, according to results of reverse transcription-polymerase chain reaction and northern blotting.⁴ The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders.⁴

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货号：

APR-012-0.2ml

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询价

0.2ml

25ul

50ul

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