ARAP3 (FITC)

FITC

Recombinant protein corresponding to aa163-320 from human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3.

Suitable for use in FLISA. Other applications not tested.

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in FLISA. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human ARAP3.

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (Centaurin-delta-3) (Cnt-d3), ARAP3, CENTD3

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