一 产品介绍
CD24由红细胞、粒细胞、单核细胞、淋巴细胞和树突细胞表达。成年小鼠骨髓和脾脏中的未成熟B细胞表达高水平的CD24,而成熟外周B细胞表达中等水平的CD24。CD24的表达已被用于分辨小鼠骨髓中B细胞淋巴细胞生成的阶段。据报道,P-选择素(CD62P)与CD24结合。CD24通常在人类肿瘤中过度表达。在癌症中,CD24是细胞迁移、侵袭和增殖的调节剂。
二 产品详情
产品货号 | BE0360 |
产品规格 | 1/5/25/50/100mg |
抗体亚型 | Rat IgG2b, κ |
推荐同型对照 | InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(货号:BE0090) |
推荐抗体稀释液 | InVivoPure™ pH7.0 Dilution Buffer(货号:IP0070) |
免疫原 | C57BL/10 mouse splenic T cells |
应用 | in vivo administration、Immunohistochemistry (frozen) Immunohistochemistry (paraffin)、Immunofluorescence、Flow cytometry |
产品形式 | PBS , pH 7.0 Contains no stabilizers or preservatives |
内毒素水平 | <2EU/mg (<0.002EU/μg) 使用 LAL gel clotting 测定 |
纯度 | >95% Determined by SDS-PAGE |
无菌处理 | 0.2 μM filtered |
生产形式 | 从组织培养上清液中纯化得到。 |
纯化形式 | Protein G |
RRID | AB_2894779 |
分子量大小 | 150 kDa |
保存条件 | 抗体原溶液应保存在4°C条件下,不要冷冻保存。 |
三 已发表文献
用途 | 已发表文献 |
in vivo administration | Kim, T. S., et al. (2015). “Stress-associated erythropoiesis initiation is regulated by type 1 conventional dendritic cells.” J Clin Invest 125(10): 3965-3980 |
in vivo administration | Shapira, S., et al. (2015). “Delayed Wound Healing in Heat Stable Antigen (HSA/CD24)-Deficient Mice.” PLoS One 10(10): e0139787 |
Immunohistochemistry (frozen) | Chen, C. Y., et al. (2009). “Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24.” Endocrinology 150(1): 492-499. |
Immunohistochemistry (frozen) | Liu, J. Q., et al. (2007). “CD24 on the resident cells of the central nervous system enhances experimental autoimmune encephalomyelitis.” J Immunol 178(10): 6227-6235 |
Immunohistochemistry (frozen) | Koni, P. A. and R. A. Flavell (1999). “Lymph node germinal centers form in the absence of follicular dendritic cell networks.” J Exp Med 189(5): 855-864 |
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