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BioXcell特色产品推荐之:InVivoMAb anti-mouse CD24(clone M1/69)

时间:2022-05-03 18:57:30
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一 产品介绍
CD24由红细胞、粒细胞、单核细胞、淋巴细胞和树突细胞表达。成年小鼠骨髓和脾脏中的未成熟B细胞表达高水平的CD24,而成熟外周B细胞表达中等水平的CD24。CD24的表达已被用于分辨小鼠骨髓中B细胞淋巴细胞生成的阶段。据报道,P-选择素(CD62P)与CD24结合。CD24通常在人类肿瘤中过度表达。在癌症中,CD24是细胞迁移、侵袭和增殖的调节剂。

 


二 产品详情

产品货号 BE0360
产品规格 1/5/25/50/100mg
抗体亚型 Rat IgG2b, κ
推荐同型对照 InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin(货号:BE0090
推荐抗体稀释液 InVivoPure™ pH7.0 Dilution Buffer(货号:IP0070
免疫原 C57BL/10 mouse splenic T cells
应用 in vivo administration、Immunohistochemistry (frozen) Immunohistochemistry (paraffin)、Immunofluorescence、Flow cytometry
产品形式 PBS , pH 7.0 Contains no stabilizers or preservatives
内毒素水平 <2EU/mg (<0.002EU/μg) 使用 LAL gel clotting 测定
纯度 >95% Determined by SDS-PAGE
无菌处理 0.2 μM filtered
生产形式 从组织培养上清液中纯化得到。
纯化形式 Protein G
RRID AB_2894779
分子量大小 150 kDa
保存条件 抗体原溶液应保存在4°C条件下,不要冷冻保存。

 
三 已发表文献

用途 已发表文献
in vivo administration Kim, T. S., et al. (2015). “Stress-associated erythropoiesis initiation is regulated by type 1 conventional dendritic cells.” J Clin Invest 125(10): 3965-3980
in vivo administration Shapira, S., et al. (2015). “Delayed Wound Healing in Heat Stable Antigen (HSA/CD24)-Deficient Mice.” PLoS One 10(10): e0139787
Immunohistochemistry (frozen) Chen, C. Y., et al. (2009). “Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24.” Endocrinology 150(1): 492-499.
Immunohistochemistry (frozen) Liu, J. Q., et al. (2007). “CD24 on the resident cells of the central nervous system enhances experimental autoimmune encephalomyelitis.” J Immunol 178(10): 6227-6235
Immunohistochemistry (frozen) Koni, P. A. and R. A. Flavell (1999). “Lymph node germinal centers form in the absence of follicular dendritic cell networks.” J Exp Med 189(5): 855-864

 

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