流式应用精选---微核检测（体内&体外）

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文章名称	样本	仪器型号	备注
Assessment of the Genotoxic Potential of Azidothymidine in the Comet,Micronucleus, and Pig-a Assay	Bone Marrow and Peripheral Blood	FACS Canto II	Azidothymidine抗病毒药物（HIV治疗），药物的遗传毒性评价
Assessment of the in vivo genotoxicity of isomers of dinitrotoluene using the alkaline Comet and peripheral blood micronucleus assays	Peripheral blood	Beckman Coulter	dinitrotoluene二硝基甲苯情况下对微核的影响
Assessment of Genotoxicity Induced by 7,12-Dimethylbenz(a)anthracene or Diethy lnitro samine in the Pig-a, Micronucleusand Comet Assays Integrated into28-DayRepeatDoseStudies	Blood samples (60 uL)	BD FACS Canto II	蒽对遗传毒性和细胞微核的影响
Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage	venous blood	FACSCalibur	染色体损伤
Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines	fromtheapproximately 5ml TK6 cell cultures or 3ml of CHO cell suspension	FACSCanto II	谷物中的赭曲霉素A致癌影响研究
Cross-Species Genetic Toxicity Assessment Accomplished by Flow Cytometric Analysis of Blood	Peripheral blood sample	FACSCalibur	遗传毒性
Cytotoxic and genotoxic effect of the [ 166 Dy]Dy/ 166 Ho-EDTMP in vivo generator system in mice	in the murine peripheral blood	FACScan	放射性同位素标记化合物对微核的影响
Dose–response relationship of temozolomide, determined by the Pig-a,comet, and micronucleus assay	peripheral blood	FACSCanto II	temozolomide抗肿瘤药物的毒理评价
Enumeration of micronucleated CD71-positive human reticulocytes with a single-laser flow cytometer	malaria-infected rat blood samples and human blood samples	FACSCalibur	微核的单激光检测
Exercise-induced protection of bone marrow cells following exposure to radiation	blood was collected by cardiac puncture	Beckman Coulter	辐射
Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: I. Intra- and Interlaboratory Comparison with Microscopic Scoring	Blood/bone marrow sample	BD-FACSCalibur	流式方法和镜检方法的对比
Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: II. An Efficient Method of Monitoring Chromosomal Damage in the Rat	Blood sample	FACSCalibur, FACSort, and FACScan	染色体损伤的检测
Flow Cytometric Method for Scoring Rat Liver Micronuclei With Simultaneous Assessments of HepatocyteProliferation	peripheral blood	BD FACSCalibur	环境影响肝再生的研究
Genetic Susceptibility to Benzene-induced Toxicity: Role of NADPH:Quinone Oxidoreductase-1 1	Blood sample		苯环药物带来的遗传毒性检测
Genotoxicity assessment of an energetic propellant compound,3-nitro-1,2,4-triazol-5-one (NTO)	Rat peripheral blood	Beckman Coulter	energetic propellant compound高能推进剂化合物对遗传毒性的影响
Genotoxicity assessment of water soluble fractions of biodiesel and its diesel blends using the Salmonella assay and the in vitro MicroFlow ? kit (Litron) assay		BD FACSCalibur	柴油&柴油调和剂处理完后的样本的微核检测
Integration of Mutation and Chromosomal \Damage Endpoints into 28-Day Repeat Dose Toxicology Studies	peripheral blood	FACSCalibur	细胞毒性引起的DNA染色体损伤
Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay	mouse L5178Y cell	BD FacsCalibur	化合物带来的细胞毒性检测
L5178Y cells were treated over a range of chemical concentrations in culture medium, one 25-cm 2 flask per concentration.	mouse blood	FACSVantage	化合物对细胞毒性的影响
Micronucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans	malaria-infected rat blood samples and human blood samples	FACSCalibur	DNA损伤检测
Micronucleated erythrocyte frequency in control and azidothymidine-treated Tk +/+ , Tk +/− and Tk −/− mice	Blood samples	FACSort	azidothymidine抗病毒药物研发过程中，对细胞微核的药物毒理检测
Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens	Blood sample	FACSCalibur	Prototypical Mutagens原型变诱剂对微核发生的影响
Radiation sensitivity and genomic instability in the hematopoietic system: Frequencies of micronucleated reticulocytes in whole-body X-irradiated BALB/c and C57BL/6 mice	One hundred to 200 microliters of blood was obtained from ether-anesthetized mice by orbital sinus bleeding	FACScan	辐射引起的微核检测
Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose–response and time-course profiles measured by flow cytometry	Blood collection occurred via an incision to the tail vein.(Mouse)	FACSCalibur	γ射线辐射引起的微核检测
VALIDATING HIGH-THROUGHPUT MICRONUCLEUS ANALYSIS OF PERIPHERAL RETICULOCYTES FOR RADIATION BIODOSIMETRY: BENCHMARK AGAINST DICENTRIC AND CBMN ASSAYS IN A MOUSE MODEL	Heparinized blood samples	FACSCalibur	辐射剂量对细胞毒性影响的研究
Male Mice Deficient in Microsomal Epoxide Hydrolase Are Not Susceptible to Benzene-Induced Toxicity	mouse blood	FACSVantage	mEH与多种癌症易感性相关联