Rabbit anti-BRD4 Antibody, Affinity Purified

Unconjugated

Antibody was affinity purified using an epitope specific to BRD4 immobilized on solid support. The epitope recognized by A301-985A100 maps to a region between residue 1312 and 1362 of human bromodomain-containing protein 4 using the numbering given in entry NP_490597.1 (GeneID 23476).Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.

BRD4

Human

兔

Between 1312 and C-terminus

Bromodomain-containing protein 4 (BRD4) contains 2 bromo-domains. Bromo-domains are found in chromatin-associating proteins and can interact specifically with acetylated lysine. BRD4 is described as a chromatin adaptor and has been shown to bind acetylated chromatin. It was originally identified as MCAP (mitotic chromosome associated protein) due to its association with mitotic chromosomes. BRD4 also associates with several transcription complexes such as the Mediator complexes and P-TEFb complexes and is considered to function as a transcriptional co-factor.

IgG

Polyclonal

Antigen Affinity Purified

1000 µg/ml

Liquid

兔抗溴结构域蛋白4抗体，三柠檬酸盐/磷酸盐缓冲液（含0.09%叠氮化钠溶液）

BRD4

IHC, Immunohistochemistry (IHC),Immunohistochemistry (IHC),IP, Immunoprecipitation (IP),Immunoprecipitation (IP),WB Western Blot (WB),Western Blot (WB)

bromodomain-containing protein 4; CAP; chromosome-associated protein; HUNK1; HUNKI; MCAP; Protein HUNK1

23476

O60885