caspase-1 substrate

Caspase-1 substrate is an IL-1β convertase substrate. The Caspase-1 substrate sequence (NEAYVHDAPVRSLN) corresponds to the native cleavage site C-terminal to Asp-116 of the precursor IL-1β. Also functions as a competitive inhibitor of caspase-1.

1584.7

≥93%

caspase-1 substrate is to inhibit the cleavage of the IL-1β precursor by ICE

IL-1B convertase substrate; NEAYVHDAPVRSLN

C68H105N21O23