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对比
咨询纯度：
Affinity purified on immobilized antigen.
Affinity purified on immobilized antigen.
反应种属：
H, M, R
H, M, R
产品介绍
产品信息
纯化方式
Affinity purified on immobilized antigen.
宿主
Rabbit
免疫原
Peptide (C)EKNKELRFKTKRE, corresponding to amino acid residues 208-220 of rat CACNG4 (Accession Q8VHW9). Intracellular, C-terminus.
简单描述
A Rabbit Polyclonal Antibody to CACNG4 (CaVγ4) Subunit
商品描述
Anti-CACNG4 Antibody (#ACC-114) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunocytochemistry applications. It has been designed to recognize CaVγ4 from rat, mouse, and human samples.
同种型
Rabbit IgG.
纯度
Affinity purified on immobilized antigen.
形式
Lyophilized
组成成分
抗蛋白抗体
基因
CACNG4
应用
实验应用
ICC, WB
反应种属
H, M, R
背景
别名
CaVγ4, Voltage-dependent calcium channel gamma-4 subunit, TARP gamma-4, Transmembrane AMPAR regulatory protein gamma-4
背景
Voltage dependent Ca2+ channels (CaV channels) are pivotal players in many physiological roles such as secretion, contraction migration and excitation1.
They are composed of several subunits; α1, β, α2δ and γ. CaV channels were originally divided into six physiological types: L, N, P, Q, R, and T type2.
L-type calcium channels are composed of five subunits. Cavγ4, represents one of these subunits, and is one of several γ subunit proteins. It is an integral membrane protein that is thought to stabilize the Ca2+ channel in an inactive (closed) state. The encoding gene is a member of the neuronal Ca2+ channel γ subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes3.
Cavγ4, along with Cavγ2, Cavγ3 and Cavγ8 have been associated with AMPA receptors and have been shown to modulate the trafficking of receptors to the plasma membrane as well as electrophysiological key properties4.
They are composed of several subunits; α1, β, α2δ and γ. CaV channels were originally divided into six physiological types: L, N, P, Q, R, and T type2.
L-type calcium channels are composed of five subunits. Cavγ4, represents one of these subunits, and is one of several γ subunit proteins. It is an integral membrane protein that is thought to stabilize the Ca2+ channel in an inactive (closed) state. The encoding gene is a member of the neuronal Ca2+ channel γ subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes3.
Cavγ4, along with Cavγ2, Cavγ3 and Cavγ8 have been associated with AMPA receptors and have been shown to modulate the trafficking of receptors to the plasma membrane as well as electrophysiological key properties4.
制备和贮存
溶解方法
25 µl, 50 µl or 0.2 ml double distilled water (DDW), depending on the sample size.
保存方式
The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
数据库链接
Entrez-Gene ID
140725
UniProt ID
Q8VHW9
研究资源识别码
AB_2340908.
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危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)