BD Pharmingen™ Purified Mouse Anti-Human CD15

CD15

Mouse BALB/c IgM, κ

U-937 histiocytic cell line

Reacts with the Le[x] blood group antigen, lacto-N-fucopentaose III or the CD15 antigen. The Le[x] determinant is expressed on normal cells and tissues of diverse origin, including myelomonocytic cells, myoepithelial cells in prostate, glandular epithelial cells including breast, renal cell and hepatocellular carcinomas, lung and urinary bladder adenocarcinomas and Reed-Sternberg cells in Hodgkin's disease.

Reacts with the Le[x] blood group antigen, lacto-N-fucopentaose III or the CD15 antigen. The Le[x] determinant is expressed on normal cells and tissues of diverse origin, including myelomonocytic cells, myoepithelial cells in prostate, glandular epithelial cells including breast, renal cell and hepatocellular carcinomas, lung and urinary bladder adenocarcinomas and Reed-Sternberg cells in Hodgkin"s disease.

Mouse BALB/c IgM, κ

克隆 MMA (RUO)

1.0 mg/ml

Flow cytometry (Routinely Tested), Dot Blot, ELISA, Functional assay, Immunohistochemistry-formalin (antigen retrieval required) (Reported)

Human (QC Testing)

CD15

Aqueous buffered solution containing ≤0.09% sodium azide.

研发参考(13) 1. Bevilacqua MP, Nelson RM. Endothelial-leukocyte adhesion molecules in inflammation and metastasis. Thromb Haemost. 1993 July; 70(1):152-154. (Biology). 2. García Prats MD, López Carreira M, Martínez-González MA, Ballestín C, Gil R, De Prada I. Granular cell basal cell carcinoma. Light microscopy, immunohistochemical and ultrastructural study. Virchows Arch A Pathol Anat Histopathol. 1993; 422(2):173-177. (Biology). 3. Grignon DJ, Ro JY, Ayala AG, Johnson DE, Ordóñez NG. Primary adenocarcinoma of the urinary bladder. A clinicopathologic analysis of 72 cases. Cancer. 1991 April; 67(8):2165-2172. (Biology). 4. Groves RW, Allen MH, Ross EL, Ahsan G, Barker JN, MacDonald DM. Expression of selectin ligands by cutaneous squamous cell carcinoma. Am J Pathol. 1993; 143(4):1220-1225. (Biology). 5. Hanjan SN, Kearney JF, Cooper MD. A monoclonal antibody (MMA) that identifies a differentiation antigen on human myelomonocytic cells. Clin Immunol Immunopathol. 1982 May; 23(2):172-188. (Biology). 6. Hsu SM, Huang LC, Hsu PL, et al. Biochemical and ultrastructural study of Leu M1 antigen in Reed-Sternberg cells: comparison with granulocytes and interdigitating reticulum cells. J Natl Cancer Inst. 1986 August; 77(2):363-370. (Biology). 7. Ma CK, Zarbo RJ, Frierson HF Jr, Lee MW. Comparative immunohistochemical study of primary and metastatic carcinomas of the liver. Am J Clin Pathol. 1993 May; 99(5):551-557. (Biology). 8. McCormick BA, Zetter BR. Adhesive interactions in angiogenesis and metastasis. Pharmacol Ther. 1992; 53(2):239-260. (Biology). 9. Narita T, Funahashi H, Satoh Y, Watanabe T, Sakamoto J, Takagi H. Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer. Cancer. 1993 May; 71(10):3044-3053. (Biology). 10. O'Hara CJ, Corson JM, Pinkus GS, Stahel RA. ME1. A monoclonal antibody that distinguishes epithelial-type malignant mesothelioma from pulmonary adenocarcinoma and extrapulmonary malignancies. Am J Clin Pathol. 1990 Februaru; 136(2):421-428. (Biology). 11. Paties C, Taccagni GL, Papotti M, Valente G, Zangrandi A, Aloi F. Apocrine carcinoma of the skin. A clinicopathologic, immunocytochemical, and ultrastructural study. Cancer. 1993 January; 71(2):375-381. (Biology). 12. Torii A, Nakayama A, Harada A, et al. Expression of the CD15 antigen in hepatocellular carcinoma. Cancer. 1993 June; 71(2):3864-3867. (Biology). 13. Zhou Q, Moore KL, Smith DF, Varki A, McEver RP, Cummings RD. The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells. J Cell Biol. 1991; 115(2):557-564. (Biology).

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