InVivoMAb anti-mouse CD4
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InVivoMAb anti-mouse CD4

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品牌: BioXcell
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    反应种属:
    mouse
    mouse
    实验应用:
    false
    false
    产品介绍
    产品信息
    克隆号
    GK1.5
    克隆类别
    单抗
    浓度
    Lot specific,typically between 4-11 mg/ml

    Product Details

    The GK1.5 monoclonal antibody reacts with the mouse CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The GK1.5 antibody has been shown to compete with clones YTS 177 and YTS 191 for CD4 binding.

    Specifications

    Isotype Rat IgG2b, κ
    Recommended Isotype Control(s)InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin
    Recommended Dilution BufferInVivoPure pH 6.5 Dilution Buffer
    Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
    Immunogen Mouse CTL clone V4
    Reported Applicationsin vivo CD4+ T cell depletion
    Flow cytometry
    Western blot
    Formulation PBS, pH 6.5
    Contains no stabilizers or preservatives
    Endotoxin <2EU/mg (<0.002EU/μg)
    Determined by LAL gel clotting assay
    Purity >95%
    Determined by SDS-PAGE
    Sterility 0.2 µm filtration
    Production Purified from cell culture supernatant in an animal-free facility
    Purification Protein G
    RRIDAB_1107636
    Molecular Weight 150 kDa
    Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
    组成成分
    抗鼠细胞表面膜蛋白抗体,磷酸盐缓冲液
    应用
    实验应用
    false
    反应种属
    mouse
    背景
    研究领域
    Immunology
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    货号:
    BE0003-1-1MG
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