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产品介绍
产品信息
克隆号
GK1.5

克隆类别
单抗

浓度
Lot specific,typically between 4-11 mg/ml

Product Details
The GK1.5 monoclonal antibody reacts with the mouse CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The GK1.5 antibody has been shown to compete with clones YTS 177 and YTS 191 for CD4 binding.Specifications
Isotype | Rat IgG2b, κ |
---|---|
Recommended Isotype Control(s) | InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin |
Recommended Dilution Buffer | InVivoPure pH 6.5 Dilution Buffer |
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Immunogen | Mouse CTL clone V4 |
Reported Applications | in vivo CD4+ T cell depletion Flow cytometry Western blot |
Formulation | PBS, pH 6.5 Contains no stabilizers or preservatives |
Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity | >95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from cell culture supernatant in an animal-free facility |
Purification | Protein G |
RRID | AB_1107636 |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
抗鼠细胞表面膜蛋白抗体,磷酸盐缓冲液

应用
实验应用
false

反应种属
mouse

背景
研究领域
Immunology
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