InVivoPlus anti-mouse CD4
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InVivoPlus anti-mouse CD4

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品牌: BioXcell
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    反应种属:
    mouse
    mouse
    来源宿主:
    产品介绍
    产品信息
    宿主
    克隆号
    GK1.5
    克隆类别
    单抗

    Product Details

    The GK1.5 monoclonal antibody reacts with the mouse CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The GK1.5 antibody has been shown to compete with clones YTS 177 and YTS 191 for CD4 binding.

    Specifications

    Isotype Rat IgG2b, κ
    Recommended Isotype Control(s)InVivoPlus rat IgG2b isotype control, anti-keyhole limpet hemocyanin
    Recommended Dilution BufferInVivoPure pH 6.5 Dilution Buffer
    Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
    Immunogen Mouse CTL clone V4
    Reported Applicationsin vivo CD4+ T cell depletion
    Flow cytometry
    Western blot
    Formulation PBS, pH 6.5
    Contains no stabilizers or preservatives
    Aggregation* <5%
    Determined by DLS
    Purity >95%
    Determined by SDS-PAGE
    Sterility 0.2 µm filtration
    Production Purified from cell culture supernatant in an animal-free facility
    Purification Protein G
    RRIDAB_1107636
    Molecular Weight 150 kDa
    Murine Pathogen Tests* Ectromelia/Mousepox Virus: Negative
    Hantavirus: Negative
    K Virus: Negative
    Lactate Dehydrogenase-Elevating Virus: Negative
    Lymphocytic Choriomeningitis virus: Negative
    Mouse Adenovirus: Negative
    Mouse Cytomegalovirus: Negative
    Mouse Hepatitis Virus: Negative
    Mouse Minute Virus: Negative
    Mouse Norovirus: Negative
    Mouse Parvovirus: Negative
    Mouse Rotavirus: Negative
    Mycoplasma Pulmonis: Negative
    Pneumonia Virus of Mice: Negative
    Polyoma Virus: Negative
    Reovirus Screen: Negative
    Sendai Virus: Negative
    Theiler’s Murine Encephalomyelitis: Negative
    Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
    * Additional quality control measures for our InVivoPlus™ products include advanced binding validation, murine pathogen screening, protein aggregation screening, and ultra-low endotoxin levels. The superior quality of our InVivoPlus™ products will meet and exceed the strict demands and rigorous standards required for in vivo research. Learn more about the InVivoPlus™ difference here.
    组成成分
    辅助受体蛋白抗体,磷酸盐缓冲液
    应用
    反应种属
    mouse
    背景
    研究领域
    Immunology
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    货号:
    BP0003-1-5MG
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