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CD68 (D4B9C) XP ® Rabbit mAb
CD68 (D4B9C) XP ® Rabbit mAb
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CD68 (D4B9C) XP ® Rabbit mAb

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品牌： CST
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    反应种属：
    Human
    Human
    来源宿主：
    Rabbit
    Rabbit
    产品介绍
    产品信息
    抗原名称
    CD68
    来源纯化
    通过采用重组人 CD68 蛋白对动物进行免疫接种来产生单克隆抗体。
    宿主
    Rabbit
    简单描述
    Monoclonal Antibody for studying CD68. Cited in 98 publications. Validated for IHC, IF, F, F. Available in 2 sizes. Highly specific and rigorously validated in-house, CD68 (D4B9C) XP® Rabbit Monoclonal Antibody (CST #76437) is ready to ship.
    商品描述

    Product Usage Information

    ApplicationDilution
    Immunohistochemistry (Paraffin)1:200 - 1:800
    Immunofluorescence (Immunocytochemistry)1:400 - 1:800
    Flow Cytometry (Fixed/Permeabilized)1:200 - 1:800
    Flow Cytometry (Live)1:200 - 1:800
    研究领域
    癌症,纤维化,免疫学和肿瘤学,神经科学,
    应用
    反应种属
    Human
    目标/特异性

    Specificity/Sensitivity

    CD68 (D4B9C) XP® Rabbit mAb 可识别 CD68 总蛋白的内源水平。

    物种反应性：

    人, 猴

    敏感性
    Endogenous
    背景
    背景
    CD68 （巨噬唾液酸蛋白）是由单核细胞和巨噬细胞表达并且常用作其标志物的重度糖基化的跨膜蛋白 (1,2)。它存在于质膜以及内体膜和溶酶体膜上 (1-3)。据称它结合 OxLDL 并且已被观察为同型二聚体形式 (3,4)。 1.Rabinowitz, S.S. and Gordon, S. (1991) J Exp Med 174, 827-36. 2.Holness, C.L. and Simmons, D.L. (1993) Blood 81, 1607-13. 3.Ramprasad, M.P. et al. (1995) Proc Natl Acad Sci U S A 92, 9580-4. 4.Ramprasad, M.P. et al. (1996) Proc Natl Acad Sci U S A 93, 14833-8.
    研究领域
    癌症,纤维化,免疫学和肿瘤学,神经科学,
    翻译后修饰
    Unmodified
    制备和贮存
    保存方式
    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.For a carrier free (BSA and azide free) version of this product see product #26042.
    数据库链接
    Entrez-Gene ID
    968
    UniProt ID
    P34810

    参考图片

    Confocal immunofluorescent analysis of THP-1 (left) and Jurkat (right) cells using CD68 (D4B9C) XP® Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). Projected images from a z-stack series are shown.

    Immunohistochemical analysis of paraffin-embedded human tonsil using CD68 (D4B9C) XP® Rabbit mAb.

    Immunohistochemical analysis of paraffin-embedded THP-1 (left) and Jurkat (right) cell pellets using CD68 (D4B9C) XP® Rabbit mAb.

    Flow cytometric analysis of human peripheral blood mononuclear cells co-stained with anti-human CD14 using CD68 (D4B9C) XP® Rabbit mAb (right) compared to a concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (left). Anti-rabbit IgG (H+L), F(ab')2 Fragment (Alexa Fluor® 488 Conjugate) #4412 was used as a secondary antibody.

    Flow cytometric analysis of Jurkat cells (blue) and THP-1 cells (green) using CD68 (D4B9C) XP® Rabbit mAb. Anti-rabbit IgG (H+L), F(ab')2 Fragment (Alexa Fluor® 488 Conjugate) #4412 was used as a secondary antibody.

    Immunohistochemical analysis of paraffin-embedded human serous papillary carcinoma of the ovary using CD68 (D4B9C) XP® Rabbit mAb.

    Immunohistochemical analysis of paraffin-embedded human lung carcinoma using CD68 (D4B9C) XP® Rabbit mAb.

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    货号：
    76437S
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    20ul
    100ul
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    当前规格1件起购 
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