CD8α Recombinant Mouse mAb (SDT-126-8)
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CD8α Recombinant Mouse mAb (SDT-126-8)

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品牌: STARTER
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    反应种属:
    Hu
    Hu
    来源宿主:
    Mouse
    Mouse
    展开
    产品介绍
    产品信息
    纯化方式
    Protein G
    抗原名称
    CD8α
    宿主
    Mouse
    免疫原
    Synthetic Peptide
    同种型
    IgG1,k
    克隆号
    SDT-126-8
    浓度
    2 mg/ml
    性状
    Liquid
    缓冲体系
    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
    产品类型
    Mouse mAb
    应用
    实验应用
    IHC-P
    反应种属
    Hu
    稀释度
    • IHC-P

      1:2000
    背景
    别名
    T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain, MAL, CD8a
    背景

    CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy.In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

    细胞定位
    Cell membrane
    制备和贮存
    保存方式

    12 months from date of receipt / reconstitution, -20 °C as supplied

    数据库链接
    Accession

    参考图片

    IHC shows positive staining in paraffin-embedded human stomach. Anti-CD8α antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD8α antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

    IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD8α antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.

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    货号:
    S0B2148-10ul
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    1 ml
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