Product Details

The 3.3 monoclonal antibody reacts with CD96, also known as TACTILE (T cell activation increased late expression). CD96 is a type I transmembrane glycoprotein and member of the Ig superfamily. CD96 is expressed at low levels on resting NK cells and T cells and at high levels on activated NK and T cells. CD96 binds to its ligand, CD155 to mediate NK cell adhesion to target cells and cytotoxicity. CD96 has recently been identified as a novel target for cancer immunotherapy and has been shown to play a role in metastasis. The 3.3 antibody has been shown to suppress primary tumor growth in a number of experimental mouse tumor models.

Specifications

Isotype	Rat IgG1, λ
Recommended Isotype Control(s)	InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
Recommended Dilution Buffer	InVivoPure pH 7.0 Dilution Buffer
Conjugation	This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
Immunogen	Not available or unknown
Reported Applications	in vivo CD96 blocking in vitro CD96 blocking Flow cytometry
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Endotoxin	<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay
Purity	>95% Determined by SDS-PAGE
Sterility	0.2 μM filtered
Production	Purified from cell culture supernatant in an animal-free facility
Purification	Protein G
RRID	AB_2894757
Molecular Weight	150 kDa
Storage	The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

组成成分

抗CD96（跨膜蛋白）抗体，磷酸盐缓冲液

应用

反应种属

Mouse

背景

研究领域

Cancer Biology, Cell Migration & Adhesion

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货号：

BE0337-1MG

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