cGAS (D-9)

鼠

cGAS抗体(D-9)是小鼠单克隆IgG2a κ, 在14篇文献中引用，规格为200 µg/ml特异性抗原位于human物种的的N-terminus附近的氨基酸19-42之间cGAS 抗体 (D-9) 推荐用于WB, IP, IF, IHC(P) 和 ELISA，检测human 来源的 cGAS; not recommended for detection of cGAS of mouse and rat origin; 可能与 an unknown protein of similar size in mouse and rat产生交联反应抗-cGAS 抗体 (D-9) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取cGAS (D-9): sc-515777的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP and m-IgG2a BP-HRP 是 cGAS Antibody (D-9) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供cGAS Antibody (D-9) (见下方订购信息). 查看产品引用文献(14) The presence of foreign DNA in the cytoplasm induces an antiviral host immune response. DNA in the cytoplasm triggers the production of interferons by activating and synthesis of second messenger cyclic guanosine monophosphate-adenosine monophosphate (cyclic GMP-AMP, or cGAMP). cGAS (cyclic GMP-AMP synthase), also known as MB21D1 (Mab-21 domain containing 1), h-cGAS or C6orf150, is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor. cGAS binds to cytosolic DNA, which leads to cGAMP synthesis and activation of TMEM173, thereby trigger type-I interferon production. Expressed in monocytic cell line THP1, cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® and Odyssey® are registered trademarks of L

Replacement monoclonal antibody for: sc-245858, sc-245860.

核苷酸转移酶抗体，磷酸盐缓冲液

HumanMB21D1