霍乱毒素B亚单位(FITC conjugated)

霍乱毒素B亚单位(FITC conjugated)

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品牌: Absin
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    分子量:
    11kd
    11kd
    CAS号:
    131096-89-4
    131096-89-4
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    产品介绍
    产品信息
    商品描述

    Cholera toxin (CTB,霍乱毒素B亚基)belongs to the AB5 –subunit family oftoxins.The native hexameric protein has a molecular mass of ~85 kDa and contains two subunits. It consists of a single A subunit (~27.2 kDa), responsible for the ADP-ribosylation activity, and five B subunits(~11.6 kDa each), which are arranged as a pentameric ring with an apparent 5-fold symmetry and are associated with the cell surface receptor binding and subsequent internalization (transmembrane transport)of the enzymatic component.

    分子量
    11kd
    纯度

    ≥95%

    浓度
    See the label for details.
    外观
    liquid
    应用
    反应种属
    Human;Mouse;Rat;Pig;Zebrafish;Dog;Monkey;Fish
    注意事项
    The B subunit is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. The cholera toxin B subunit (CTB) attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. The B subunit has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Recently it has been widely used as a marker of membrane lipid rafts, which are membrane microdomains enriched with cholestrol and sphingolipids. These lipid rafts have an important role in cell signaling and protein trafficking.
    背景
    别名
    霍乱毒素B亚基-FITC、CHOLERA TOXIN B SUBUNIT-FITC、CTB-FITC、 Cholera Toxin B subunit-FITC、CTxB-FITC、Choleragenoid-FITC
    技术指标

    Format:Recombinant Source:E.coli Sodium azide:Not add.

    CAS号
    131096-89-4
    制备和贮存
    保存方式
    store at -20 ℃ for one year.
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    货号:
    abs80003-1mg
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    询价
    优宁维现货
    1mg
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    当前规格1件起购 
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