
产品介绍
产品信息
宿主
mouse

简单描述
cylindromatosis 1抗体(E-10)是小鼠单克隆IgG2a κ, 在46篇文献中引用,规格为200 µg/mlraised against the C-terminal 419 amino acids of cylindromatosis 1 of human origin抗-cylindromatosis 1 抗体 (E-10) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 cylindromatosis 1抗-cylindromatosis 1 抗体 (E-10) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取cylindromatosis 1 (E-10): sc-74435的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP 是 cylindromatosis 1 Antibody (E-10) for WB 的首选应用二抗。这个产品以套装形式提供 cylindromatosis 1 Antibody (E-10) (参照下方订购信息).
查看产品引用文献(45) Familial cylindromatosis is an autosomal dominant genetic predisposition to multiple benign neoplasms of the skin known as cylindromas. These cylindromas may become infected, resulting in disfigurement and discomfort. In severe cases, ulcerated cylindromas are only treatable by reconstructive surgery with skin grafts. The human CYLD gene on chromosome 16q12.1 encodes the protein cylindromatosis 1. Mutations in this gene are responsible for familial cylindromatosis. The cylindromatosis 1 protein contains three cytoskeletal-associated protein-glycineconserved (CAP-GLY) domains and may function to coordinate the attachment of organelles to microtubules. Cylindromatosis 1 is expressed in brain, gonads, skeletal muscle, spleen, liver, heart, lung and leukocytes. Somatic mutations of the CYLD gene appear to play a role in the oncogenesis of tumors with cylindromatous features.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® and Odyssey® are registered trademarks of LI

克隆类别
Replacement monoclonal antibody for: sc-21286, sc-25779.

组成成分
IGG-免疫球蛋白G型抗体

基因

数据库链接
Entrez-Gene ID
1540;74256

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