Cytokeratin 18 (B23.1.)

mouse

Cytokeratin 18抗体(B23.1.)是小鼠单克隆IgG1 κ, 在1篇文献中引用，规格为200 µg/ml培养自human来源乳腺癌细胞系PMC-42推荐用于 human 来源的Cytokeratin 18 WB, IP, IF, IHC(P) 和 FCM检测看 Cytokeratin 18 (RGE53): sc-32329，可查看有标记的 Cytokeratin 18 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790目前，我们还没有完成Cytokeratin 18 抗体 (B23.1.)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(1) Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, Cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while Cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Cytokeratin 18 contains two major phosphorylation sites on Ser 33 and Ser 52. Phosphorylation of Ser 18 is essential for the association of Cytokeratin 18 with 14-3-3 proteins and is involved in keratin organization and distribution.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanKRT18

WB, IP, IF, IHC(P), FCM

3875