DLL4

Recombinant protein corresponding to aa44-345 from human Delta-like protein 4 protein.

Suitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested.

Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested.

Western Blot: 1:500-1:5000 Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human DLL4.

Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4), DLL4

Q9NR61