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DRP1 (6Z-82)
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产品介绍
产品信息
宿主
mouse
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简单描述
DRP1抗体(6Z-82)是小鼠单克隆IgG2b κ, 在20篇文献中引用,规格为100 µg/ml免疫human物种的重组DRP1推荐用于 mouse, rat 和 human 来源的DRP1 WB, IP, IF, IHC(P) 和 ELISA检测看 DRP1 (C-5): sc-271583,可查看有标记的 DRP1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790关于如何获取DRP1 (6Z-82): sc-101270的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG2b BP-HRP 和 m-IgGκ BP-HRP 是 DRP1 Antibody (6Z-82) for WB and IHC(P) 首选应用二抗. 这些试剂现在以套形式提供 DRP1 Antibody (6Z-82) (见下方订购信息).
查看产品引用文献(20) Dynamin-related protein 1 (DRP1) mediates outer mitochondrial membrane fission in mammalian cells. DRP1 is also known as Dynamin-like protein 1, (Dlp1), DVLP or Dymple. DRP1 contains the N-terminal tripartite GTP-binding domain characteristic of the Dynamin superfamily of GTPases. DRP1 exists as a T-shaped dimer which contains a head, leg and stalk. The addition of GTP induces a rearrangement of the head and stalk that generates a force that ultimately results in membrane constriction. DRP1 is ubiquitously expressed with abundant expression in skeletal muscle, heart, kidney and brain. In the cell, DRP1 localized to the perinuclear region. In mouse brain, DRP1 is highly expressed in the cerebellum with particularly high levels in cerebellar Purkinje cells. During apoptosis, DRP1 translocates from the cytosol to mitochondria and localizes to potential sites of organelle division. Cell death is averted upon DRP inhibition, suggesting a critical role for mitochondrial fission in apoptosis.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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克隆类别
Replacement monoclonal antibody for: sc-21804, sc-32898.
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组成成分
动力蛋白相关蛋白1抗体、1.0ml磷酸缓冲盐溶液(含0.1%叠氮化钠和0.1%明胶)
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基因
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数据库链接
Entrez-Gene ID
10059;74006
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