InVivoMAb anti-human EphA2

InVivoMAb anti-human EphA2

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品牌: BioXcell
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    反应种属:
    Human
    Human
    产品介绍
    产品信息

    Product Details

    The B2D6 monoclonal antibody reacts with human Ephrin type-A receptor 2 (EphA2). EphA2 is a ~130 kDa type I transmembrane glycoprotein that belongs to the receptor tyrosine kinase family. EphA2 is variably expressed by epithelial cells, dendritic cells, Langerhans cells, keratinocytes, and endothelial cells. EphA2 functions as a receptor for glycophosphatidylinositol (GPI) membrane-linked members of the Ephrin-A family, including Ephrins A1-A5. EphA2 is involved in regulating cellular growth, adhesion, migration, survival, and plays a role in angiogenesis. Its expression may be upregulated on vascular endothelium in certain breast, prostate, and colon cancers as well as on some metastatic tumor cells.

    Specifications

    Isotype Mouse IgG2b, κ
    Recommended Isotype Control(s)InVivoMAb mouse IgG2b isotype control, unknown specificity
    Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer
    Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
    Immunogen Human EphA2 isolated from Ras-transformed MCF-10A cells
    Reported Applications Immunohistochemistry (paraffin)
    Immunoprecipitation
    Functional assay
    Formulation PBS, pH 7.0
    Contains no stabilizers or preservatives
    Endotoxin <2EU/mg (<0.002EU/μg)
    Determined by LAL gel clotting assay
    Purity >95%
    Determined by SDS-PAGE
    Sterility 0.2 μM filtered
    Production Purified from cell culture supernatant in an animal-free facility
    Purification Protein A
    RRIDAB_2894761
    Molecular Weight 150 kDa
    Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
    组成成分
    IGG-免疫球蛋白G型抗体
    应用
    反应种属
    Human
    背景
    研究领域
    Cancer Biology, Cell Migration & Adhesion, Tumor Antigens
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    货号:
    BE0341-1MG
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