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InVivoMAb anti-human EphA2

产品介绍
产品信息
Product Details
The B2D6 monoclonal antibody reacts with human Ephrin type-A receptor 2 (EphA2). EphA2 is a ~130 kDa type I transmembrane glycoprotein that belongs to the receptor tyrosine kinase family. EphA2 is variably expressed by epithelial cells, dendritic cells, Langerhans cells, keratinocytes, and endothelial cells. EphA2 functions as a receptor for glycophosphatidylinositol (GPI) membrane-linked members of the Ephrin-A family, including Ephrins A1-A5. EphA2 is involved in regulating cellular growth, adhesion, migration, survival, and plays a role in angiogenesis. Its expression may be upregulated on vascular endothelium in certain breast, prostate, and colon cancers as well as on some metastatic tumor cells.Specifications
Isotype | Mouse IgG2b, κ |
---|---|
Recommended Isotype Control(s) | InVivoMAb mouse IgG2b isotype control, unknown specificity |
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Immunogen | Human EphA2 isolated from Ras-transformed MCF-10A cells |
Reported Applications | Immunohistochemistry (paraffin) Immunoprecipitation Functional assay |
Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity | >95% Determined by SDS-PAGE |
Sterility | 0.2 μM filtered |
Production | Purified from cell culture supernatant in an animal-free facility |
Purification | Protein A |
RRID | AB_2894761 |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
IGG-免疫球蛋白G型抗体

应用
反应种属
Human

背景
研究领域
Cancer Biology, Cell Migration & Adhesion, Tumor Antigens
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