FERMT1 (FITC)

FITC

Recombinant protein corresponding to aa321-420 from human fermitin family homolog 1.

Suitable for use in FLISA. Other applications not tested.

Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in FLISA. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human FERMT1.

Fermitin family homolog 1 (Kindlerin) (Kindlin syndrome protein) (Kindlin-1) (Unc-112-related protein 1), FERMT1, C20orf42 KIND1 URP1

Q9BQL6