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Fibulin-2 (3B9A11)

产品介绍
产品信息
宿主
mouse

简单描述
Fibulin-2抗体(3B9A11)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
raised against a recombinant protein corresponding to amino acids 180-440 of Fibulin-2 of human origin
推荐用于 human 来源的Fibulin-2 WB 和 ELISA检测
m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 Fibulin-2 Antibody (3B9A11) for WB首选应用二抗。这些试剂现在以套装形式提供Fibulin-2 Antibody (3B9A11) (见下方订购信息). Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

组成成分
IGG-免疫球蛋白G型抗体

基因

数据库链接
Entrez-Gene ID
2199

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