HDAC9 (B-1)

mouse

抗-Histone Deacetylase 9 (HDAC9) 抗体 B-1 是小鼠单克隆 IgM κ，Histone Deacetylase 9 (HDAC9)抗体, 在7篇文献中引用，规格为200 µg/ml特异性抗原位于human物种的HDAC9的N-terminus的氨基酸12-39之间推荐用于 mouse, rat 和 human 来源的HDAC9 isoforms 1-4 WB, IP, IF 和 ELISA检测关于如何获取Histone Deacetylase 9 (HDAC9) (B-1): sc-398003的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。目前，我们还没有完成Histone Deacetylase 9 (HDAC9) 抗体 (B-1)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(4) HDAC9 Antibody (B-1) is a high quality monoclonal HDAC9 antibody (also designated Histone Deacetylase 9 antibody) suitable for the detection of the HDAC9 protein of mouse, rat and human origin. HDAC9 Antibody (B-1) is available as the non-conjugated anti-HDAC9 antibody. In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is a critical component of transcriptional regulation and the acetylation of nucleosomal histones is a major source of this remodeling. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Several mammalian proteins function as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Conversely, the deacetylation of histones is associated with transcriptional silencing. The histone deacetylases (HDAC) include HDAC1-9. HDAC9 and HDAC9a are two alternatively spliced isoforms of HDAC9. HDAC9a is 132 amino acids shorter than HDAC9, but both isoforms contain the HDAC catalytic domain, remain capable of deacetylase activity and repress myoctye enhancer-binding factor 2-mediated transcription. HDAC9 and HDAC9a are expressed in brain, skeletal muscle, kidney, placenta and pancreas.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-10408, sc-28732, sc-30744, sc-32094, sc-32095.

MouseHdac9

m, r, h

9734;79221