LILRB1 (Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 1, CD85, CD85J, FLJ37515, ILT2, LIR-1, LIR1, MIR-7, MIR

LILRB1 (AAH15731.1, 1aa-650aa) full-length human protein.

Suitable for use in Western Blot, Immunoprecipitation. Other applications not tested.

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

IgG

Polyclonal

Purified

Suitable for use in Western Blot, Immunoprecipitation. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human LILRB1.

Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 1, CD85, CD85J, FLJ37515, ILT2, LIR-1, LIR1, MIR-7, MIR7