LRP8

Purified recombinant protein fragment corresponding to aa:extra 42-182 from human LRP8, expressed in E. coli.

Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.

This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

IgG1

6F6B6

Monoclonal

Purified

Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.

ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher.

Mouse

Hu

Recognizes human LRP8.

MCI1; LRP-8; APOER2; HSZ75190