ICAM-2 (3C4)

rat

ICAM-2 抗体 3C4 是大鼠单克隆 IgG2a，提供 200 µg/ml raised against COS cells transfected with mouse ICAM-2 推荐用于 mouse 来源的ICAM-2 IF 和 FCM检测 还可偶联FITC 用于IF, IHC(P) 和FCM 目前，我们还没有完成ICAM-2 抗体 (3C4)的首选二抗检测试剂的鉴定。这项工作正在进行中。 Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the b2a1 and b2aM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils, and when bound to ligand may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins aLb2, aMb2, a4b1, the aV family and aIIbb3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

MouseIcam2

15896