











8-9kDa (Non-Reducing)
8-9kDa (Non-Reducing)
>95% by SDS-PAGE
>95% by SDS-PAGE


8-9kDa (Non-Reducing)


>95% by SDS-PAGE









Insulin-like growth factor 1 (IGF-1) is also known as somatomedin C, IGF1A, IGFI, sulfation factor, and is a hormone similar in molecular structure to insulin. IGF-1 Protein binds to cell surface receptor IGF type 1 receptor, which abbreviated as "IGF1R" and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF-1 Protein also mediates neuroprotective mechanism. It is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.


· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1.Jansen M., et al.(1983)Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature306:609-611.

参考图片
2μg (N: non-reducing condition).
Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is less than 5ng/ml.