IGF-I Protein, Human
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IGF-I Protein, Human

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品牌: UA BIOSCIENCE
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    分子量:

    8-9kDa (Non-Reducing)

    8-9kDa (Non-Reducing)

    纯度:

    >95% by SDS-PAGE

    >95% by SDS-PAGE

    产品介绍
    产品信息
    耦联标记
    Unconjugated
    氨基酸序列
    Gly49-Ala118
    分子量

    8-9kDa (Non-Reducing)

    生物活性
    <5ng/ml
    纯度

    >95% by SDS-PAGE

    内毒素水平
    <0.1EU/μg
    性状
    Lyophilized Powder
    表达系统
    E.coli
    缓冲体系
    50mM NaAc, pH6.0.
    标签
    No Tag
    种属
    Human
    电泳JSON
    [{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/dbe28e81-e2e6-423c-94f1-1faf03159c76.png","description":"2μg (N: non-reducing condition)."}]
    背景
    别名
    IGF-I Protein, IGF1A Protein, IGFI Protein
    背景

    Insulin-like growth factor 1 (IGF-1) is also known as somatomedin C, IGF1A, IGFI, sulfation factor, and is a hormone similar in molecular structure to insulin. IGF-1 Protein binds to cell surface receptor IGF type 1 receptor, which abbreviated as "IGF1R" and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone. IGF-1 Protein also mediates neuroprotective mechanism. It is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.

    制备和贮存
    溶解方法
    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
    保存方式
    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
    文献
    文献

    1.Jansen M., et al.(1983)Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature306:609-611.

    数据库链接
    Accession

    参考图片

    2μg (N: non-reducing condition).

    Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is less than 5ng/ml.

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    货号:
    UA040055-1mg
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