IL-13 Protein, Human

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IL-13 Protein, Human

品牌： UA BIOSCIENCE

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参数

分子量：

30-35kDa

纯度：

>95% by SDS-PAGE

产品介绍

产品信息

耦联标记

Unconjugated

氨基酸序列

Gly35-Asn146, with C-terminal 8*His GPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFNGGGSHHHHHHHH

分子量

30-35kDa

生物活性

< 5ng/ml

纯度

>95% by SDS-PAGE

内毒素水平

<0.1EU/μg

性状

Lyophilized Powder

表达系统

HEK293

缓冲体系

PBS, pH7.4

标签

His Tag

种属

Human

电泳JSON

[{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/aa8b7c9d-de70-4aff-a420-c613f0d76009.png","description":"

1μg (R: reducing condition, N: non-reducing condition).

"}]

背景

别名

IL13, ALRH, BHR1, MGC116786, MGC116788, MGC116789, P600, Interleukin-13

背景

Interleukin-13 is a cytokine which is secreted by activated T lymphocytes and primarily impacts monocytes, macrophages, and B cells. Interleukin 13 is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. Recent studies have shown that human interleukin-13 has many structural similarities with human interleukin-4 and is produced by gene replication events. As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases.Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity.

制备和贮存

溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式

12 months from date of receipt, -20 to -70 °C as supplied;

6 months, -20 to -70 °C under sterile conditions after reconstitution;

1 week, 2 to 8 °C under sterile conditions after reconstitution;

Please avoid repeated freeze-thaw cycles.

文献

1. Comparative Study Protein Expr Purif . 1998 Mar;12(2):239-48.

数据库链接

Accession

P35225

参考图片

1μg (R: reducing condition, N: non-reducing condition).

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells, the EC50 for this effect is less than 5ng/ml.

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货号：

UA040113-10μg

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