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产品介绍
产品信息
宿主
鼠
克隆号
9C1
克隆类别
单抗
Product Details
The 9C1 monoclonal antibody reacts with mouse IL-9, a pleiotropic cytokine expressed by Th9 cells, Th2 cells, Th17 cells, regulatory T cells, NKT cells, ILC2s, and mast cells. IL-9 promotes mast cell and T cell proliferation, stimulates mast cell accumulation in tissues, promotes ILC survival, enhances class-switching to IgE in B cells and alters haematopoietic progenitor cell activity. Additionally, IL-9 enhances mucus production from airway epithelial cells and alters barrier function in the intestines. IL-9 is thought to contribute to asthma. The 9C1 antibody has been reported to block the bioactivity of IL-9.Specifications
| Isotype | Mouse IgG2a |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb mouse IgG2a isotype control, unknown specificity |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Mouse IL-9-OVA complex |
| Reported Applications | in vivo IL-9 neutralization |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_10950648 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
白细胞介素9蛋白抗体，磷酸盐缓冲液
应用
反应种属
mouse
背景
研究领域
Apoptosis, Cytokine and Chemokine
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危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)