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产品介绍
产品信息
宿主
亚美尼亚仓鼠
克隆号
UC7-13D5
克隆类别
单抗
Product Details
The UC7-13D5 monoclonal antibody reacts with an epitope on the mouse γ/δ TCR (gamma delta T cell receptor) complex. The γ/δ TCR is expressed by a subset of T cells found in the thymus, peripheral lymphoid tissues, intestinal epithelium, epidermis, and peritoneum. The exact function, ligand, and specificity of γ/δ TCR-expressing T cells are not completely understood. Studies suggest that these cells recognize bacterial ligands and some tumor cells in the context of MHC class I-like gene products and play a role in regulating the immune response during bacterial infection. The UC7-13D5 antibody has been shown to activate γ/δ T cells in vitro and deplete γ/δ T cells when administered in vivo.Specifications
| Isotype | Armenian Hamster IgG, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb polyclonal Armenian hamster IgG |
| Recommended Dilution Buffer | InVivoPure pH 6.0T Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Not available or unknown |
| Reported Applications | in vivo TCR γ/δ neutralization in vitro γ/δ T cell stimulation in vitro γ/δ T cell purification Functional assays Immunoprecipitation Flow cytometry |
| Formulation | PBS + 0.01% Tween, pH 6.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein A |
| RRID | AB_1107751 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
细胞受体蛋白抗体，磷酸盐缓冲液，0.01%吐温
应用
反应种属
mouse
背景
研究领域
Immunology
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危险品化学品经营许可证(不带存储) 许可证编号：沪(杨)应急管危经许[2022]202944(QY) 
营业执照(三证合一)