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InVivoPlus anti-mouse Ly6G
InVivoPlus anti-mouse Ly6G

InVivoPlus anti-mouse Ly6G

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品牌： BioXcell
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    反应种属：
    mouse
    mouse
    来源宿主：
    鼠
    鼠
    产品介绍
    产品信息
    宿主
    鼠
    克隆号
    1A8
    克隆类别
    单抗

    Product Details

    The 1A8 monoclonal antibody reacts with mouse Ly6G. Ly6G is a 21-25 kDa member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Ly6G is expressed differentially during development by cells in the myeloid lineage including monocytes, macrophages, granulocytes, and neutrophils. Monocytes typically express Ly6G transiently during development while mature granulocytes and peripheral neutrophils retain expression making Ly6G a good cell surface marker for these populations. Unlike the RB6-8C5 antibody, the 1A8 antibody reacts specifically with mouse Ly6G with no reported cross reactivity with Ly6C.

    Specifications

    Isotype Rat IgG2a, κ
    Recommended Isotype Control(s)InVivoPlus rat IgG2a isotype control, anti-trinitrophenol
    Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer
    Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
    Immunogen EL4J cells transfected with Ly6G
    Reported Applicationsin vivo neutrophil depletion
    in vivo MDSC depletion
    Immunofluorescence
    Immunohistochemistry (paraffin)
    Immunohistochemistry (frozen)
    Flow cytometry
    Formulation PBS, pH 7.0
    Contains no stabilizers or preservatives
    Endotoxin* <1EU/mg (<0.001EU/μg)
    Determined by LAL gel clotting assay
    Aggregation* <5%
    Determined by SEC
    Purity >95%
    Determined by SDS-PAGE
    Sterility 0.2 µm filtration
    Purification Protein G
    RRIDAB_1107721
    Molecular Weight 150 kDa
    Murine Pathogen Tests* Ectromelia/Mousepox Virus: Negative
    Hantavirus: Negative
    K Virus: Negative
    Lactate Dehydrogenase-Elevating Virus: Negative
    Lymphocytic Choriomeningitis virus: Negative
    Mouse Adenovirus: Negative
    Mouse Cytomegalovirus: Negative
    Mouse Hepatitis Virus: Negative
    Mouse Minute Virus: Negative
    Mouse Norovirus: Negative
    Mouse Parvovirus: Negative
    Mouse Rotavirus: Negative
    Mycoplasma Pulmonis: Negative
    Pneumonia Virus of Mice: Negative
    Polyoma Virus: Negative
    Reovirus Screen: Negative
    Sendai Virus: Negative
    Theiler’s Murine Encephalomyelitis: Negative
    Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
    * Additional quality control measures for our InVivoPlus™ products include advanced binding validation, murine pathogen screening, protein aggregation screening, and ultra-low endotoxin levels. The superior quality of our InVivoPlus™ products will meet and exceed the strict demands and rigorous standards required for in vivo research. Learn more about the InVivoPlus™ difference here.
    组成成分
    锚定细胞表面蛋白抗体，磷酸盐缓冲液
    应用
    反应种属
    mouse
    背景
    研究领域
    Cancer Biology, Immunology, Innate Immunity
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    货号：
    BP0075-1-5MG
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