L-Lactyl Lysine Rabbit Polyclonal Antibody

L-Lactyl Lysine Rabbit Polyclonal Antibody

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品牌: STARTER
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    反应种属:
    Species Independent
    Species Independent
    来源宿主:
    Rabbit
    Rabbit
    展开
    产品介绍
    产品信息
    耦联标记
    Unconjugated
    纯化方式
    Protein A
    宿主
    Rabbit
    同种型
    IgG
    浓度
    0.5 mg/ml
    性状
    Liquid
    缓冲体系
    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
    产品类型
    Polyclonal antibody
    应用
    实验应用
    WB
    反应种属
    Species Independent
    稀释度
    • WB

      1:1000
    背景
    背景

    Lysine lactylation is an emerging post-translational modification that occurs in cellular metabolism, specifically referring to the accumulation of lactic acid modifying lysine residues on histones. Lysine lactylation modifies the chromatin structure, thereby affecting gene expression. Research has found that lactylation sites are widely distributed in gene promoter regions, closely associated with gene transcriptional activation. Lysine lactylation also participates in energy metabolism processes, potentially related to the dynamic balance regulation of histone lysine acetylation.

    制备和贮存
    保存方式

    12 months from date of receipt / reconstitution, -20°C as supplied

    参考图片

    WB result of L-Lactyl Lysine Rabbit pAb
    Primary antibody: L-Lactyl Lysine Rabbit pAb at 1/1000 dilution
    Lane 1: untreated HeLa whole cell lysate 20 µg
    Lane 2: HeLa treated with 100 mM Lactate sodium for 24 hours whole cell lysate 20 µg
    Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
    Predicted MW: Multiple
    Observed MW: Multiple

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    货号:
    S0B0719-1ml
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