LAG-3/CD223 His Tag Protein, Mouse
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LAG-3/CD223 His Tag Protein, Mouse

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品牌: UA BIOSCIENCE
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    分子量:

    55-60kDa (Reducing)

    55-60kDa (Reducing)

    纯度:

    >95% by SDS-PAGE&RP-HPLC

    >95% by SDS-PAGE&RP-HPLC

    产品介绍
    产品信息
    耦联标记
    Unconjugated
    氨基酸序列

    Gly24-Glu422, with C-terminal 8*His GPGKELPVVWAQEGAPVHLPCSLKSPNLDPNFLRRGGVIWQHQPDSGQPTPIPALDLHQGMPSPRQPAPGRYTVLSVAPGGLRSGRQPLHPHVQLEERGLQRGDFSLWLRPALRTDAGEYHATVRLPNRALSCSLRLRVGQASMIASPSGVLKLSDWVLLNCSFSRPDRPVSVHWFQGQNRVPVYNSPRHFLAETFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVLGLEPVAPLTVYAAEGSRVELPCHLPPGVGTPSLLIAKWTPPGGGPELPVAGKSGNFTLHLEAVGLAQAGTYTCSIHLQGQQLNATVTLAVITVTPKSFGLPGSRGKLLCEVTPASGKERFVWRPLNNLSRSCPGPVLEIQEARLLAERWQCQLYEGQRLLGATVYAAEHHHHHHHH

    分子量

    55-60kDa (Reducing)

    纯度

    >95% by SDS-PAGE&RP-HPLC

    内毒素水平
    <0.1EU/μg
    性状
    Lyophilized powder
    表达系统
    HEK293
    缓冲体系
    PBS, pH7.4
    标签
    His Tag
    种属
    Mouse
    电泳JSON
    [{"imgUrl":"https://univ-njua.oss-cn-shanghai.aliyuncs.com/prod/202210/365d63ce5cb247d4b8d37e4a4ae74941.png","description":"1μg (R: reducing condition, N: non-reducing condition)."}]
    背景
    别名
    Lymphocyte-activation protein 3
    背景

    Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. The LAG3 is Biased expression in spleen (RPKM 15.1), lymph node (RPKM 8.3) and 12 other tissues. Lymphocyte activation gene 3 (LAG3) is an inhibitory checkpoint protein expressed on activated T effector, T regulatory, and natural killer cells. The main function of LAG3 is the regulation of immune homeostasis. Several studies have suggested its role in malignant and autoimmune diseases.

    制备和贮存
    溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

    保存方式

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

    数据库链接
    Accession

    参考图片

    1μg (R: reducing condition, N: non-reducing condition).

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    货号:
    UA010126-25ug
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