Leptin Protein, Mouse

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Leptin Protein, Mouse

品牌： UA BIOSCIENCE

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参数

分子量：

16kDa (Reducing)

纯度：

＞95% by SDS-PAGE

产品介绍

产品信息

耦联标记

Unconjugated

氨基酸序列

Val22-Cys167

分子量

16kDa (Reducing)

生物活性

<2 ng/ml

纯度

＞95% by SDS-PAGE

内毒素水平

<0.1EU/μg

性状

Lyophilized Powder

表达系统

E.coli

缓冲体系

20mM Tris, 50mM NaCl，pH 8.0

标签

No Tag

种属

Mouse

电泳JSON

[{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/0770020b-d1dd-400f-9de7-4b2253742b56","description":"

1μg (R: reducing condition, N: non-reducing condition).

"}]

背景

别名

Leptin, rRtLeptin, Obesity protein (OB), LEP

背景

Leptin is the protein product encoded by the obese (ob) gene. It is a circulating hormone produced primarily by the adipose tissue, Which is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis. Leptin deficiency or resistance can result in profound obesity, diabetes, and infertility in humans. Leptin serves as an adiposity signal to inform the brain the adipose tissue mass in a negative feedback loop regulating food intake and energy expenditure. It also plays important roles in angiogenesis, immune function, fertility, and bone formation.

制备和贮存

溶解方法

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

文献

1.Vitam Horm. 2005;71:345-72.
2.Cell Res. 2000 Jun;10(2):81-92.

参考图片

1μg (R: reducing condition, N: non-reducing condition).

Measured in a cell proliferation assay using MCF-7 Human breast cancer cells. The EC50 for this effect is less than 2ng/ml

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货号：

UA040150-10ug

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