MITF

Purified recombinant protein fragment corresponding to aa1-114 from human MITF, expressed in E. coli.

Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

IgG1

3A2E2

Monoclonal

Purified

Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.

Mouse

Hu

Recognizes human MITF.

MI; WS2; CMM8; WS2A; bHLHe32