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CD206 (C-10)

产品介绍
产品信息
宿主
mouse

简单描述
CD206/Mannose Receptor/MMR抗体(C-10)是小鼠单克隆IgG2a κ, 在10篇文献中引用,规格为200 µg/ml免疫human来源CD206位于胞外域的1090-1389氨基酸CD206/Mannose Receptor/MMR 抗体 (C-10) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 CD206抗-CD206/Mannose Receptor/MMR 抗体 (C-10) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取CD206/Mannose Receptor/MMR (C-10): sc-376232的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。目前,我们还没有完成CD206/Mannose Receptor/MMR 抗体 (C-10)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(10) CD206, also known as macrophage mannose receptor type C (MMR or MRC1), is a type I membrane receptor protein. It is an phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.For Research Use Only. Not

克隆类别
Replacement monoclonal antibody for: sc-34577, sc-48758.

组成成分
巨噬细胞甘露糖受体C型抗体、1.0ml磷酸缓冲盐溶液(含0.1%叠氮化钠和0.1%明胶)

基因

应用
反应种属
human

数据库链接
Entrez-Gene ID
4360

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