MSX1 (Homeobox Protein MSX-1, Homeobox Protein Hox-7, Msh Homeobox 1-like Protein, HOX7) (HRP)

HRP

Full length recombinant corresponding to aa216-297 from human MSX1 (NP_002439) with GST tag. MW of the GST tag alone is 26kD.

Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.

HOX7 is a 297aa novel member of homeodomain family of DNA binding domain family (meta HOX) that functions as a DNA-associated transcription factor. It has a helix-turn-helix and DNA binding domain. It plays an important role in inhibiting MYOD1 expression and is involved in epithelial-mesenchymal signaling in many organs, playing a role in limb-pattern formation. It acts as a potential repressor in cell cycle progression and as a RNA polymerase 2 transcription factor, involved in skeletal development. Northern blot analysis detects highest expression of HOX7 in heart along with other tissues like prostate and highly in dental mesenchyme during critical bud stage, placenta, etc.

IgG2a,k

1D2

Monoclonal

Purified by Protein A affinity chromatography.

Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Mouse

Hu

Recognizes human MSX1.