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品牌: CST







产品介绍
产品信息
来源纯化
Monoclonal antibodies are produced by immunizing animals with synthetic peptides corresponding to residues near the carboxy termini of human IKKβ and IκBα, or residues surrounding Glu498 of human NF-κB p65/RelA, Ser176/180 of human IKKα, Ser32 of human IκBα, Ser536 of human NF-κB p65, Ser529 of human NF-κB p65, and Ile415 of mouse NF-κB1 p105/p50; with recombinant protein specific to a central region of human IKKα protein.

简单描述
Antibody Sampler Kit for studying IkB-a/IkB-a (Ser32) phosphate/NFkB-p105 mouse/NFkB-p65/NFkB-p65 (Ser536) phosphate/IKK-beta/IKK-alpha (Ser176/Ser180) phosphate/IKK-alpha/NFkB-p65 (Ser529) phosphate in the research area.

应用
目标/特异性
Specificity/Sensitivity
Each antibody in the NF-κB Pathway Antibody Sampler Kit II detects endogenous levels of its target protein. IKKβ (D30C6) Rabbit mAb does not cross-react with other IKK family members. Phospho-IKKα/β (Ser176/180) (16A6) Rabbit mAb detects IKKα only when phosphorylated at Ser176/180 and IKKβ only when phosphorylated at Ser177/181. Phospho-NF-κB p65 (Ser529) Antibody recognizes endogenous levels of NF-κB p65 protein only when phosphorylated at Ser529. Phospho-IκBα (Ser32) (14D4) Rabbit mAb detects endogenous levels of IκBα only when phosphorylated at Ser32. NF-κB p65 (D14E12) XP® Rabbit mAb does not cross-react with other NF-κB/Rel family members. Phospho-NF-κB p65 (Ser536) (93H1) Rabbit mAb detects NF-κB p65 only when phosphorylated at Ser536. It does not cross-react with the p50 subunit or other related proteins.

数据库链接
Entrez-Gene ID
4792,18033,5970,3551,1147

UniProt ID
P25963,P25799,Q04206,O14920,O15111

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