Product Details

The HMN4-14 monoclonal antibody reacts with mouse neurogenic locus notch homolog 4 (Notch4) a member of the Notch family of type 1 transmembrane proteins. The Notch signaling pathway is a highly conserved intercellular signaling pathway. Five Notch ligands have been identified including DLL4 and Jagged2. Upon ligand binding the Notch receptor undergoes proteolysis and translocates to the nucleus ultimately activating transcription. The Notch pathway has been shown to play a role in myeloid cell proliferation, hematopoiesis, and embryonic endothelial development.

Specifications

Isotype	Armenian Hamster IgG, κ
Recommended Isotype Control(s)	InVivoMAb polyclonal Armenian hamster IgG
Recommended Dilution Buffer	InVivoPure pH 7.0 Dilution Buffer
Conjugation	This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
Immunogen	Notch4-Fc recombinant protein
Reported Applications	in vivo Notch4 blocking in vitro Notch4 stimulation Flow cytometry
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Endotoxin	<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay
Purity	>95% Determined by SDS-PAGE
Sterility	0.2 µm filtration
Production	Purified from cell culture supernatant in an animal-free facility
Purification	Protein G
RRID	AB_10948996
Molecular Weight	150 kDa
Storage	The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

组成成分

IGG-免疫球蛋白G型抗体

应用

反应种属

mouse

背景

研究领域

Immunology, Neuroscience

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货号：

BE0129-1MG

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