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p-NFκB p65 (27.Ser 536)

产品介绍
产品信息
宿主
mouse

简单描述
p-NFκB p65抗体(27.Ser 536)是小鼠单克隆IgG1 κ, 在150篇文献中引用,规格为200 µg/mlraised against a short amino acid sequence containing phosphorylated Ser 536 of NFκB p65 of human origin推荐用于 mouse, rat 和 human 来源的Ser 536 phosphorylated NFκB p65 WB, IP, IF, IHC(P) 和 ELISA检测还可偶联琼脂糖 用于IP; 偶联HRP 用于WB, IHC(P) 和ELISA可用于ChIP的TransCruz试剂(sc-136548 X, 200 µg/0.1 ml)关于如何获取p-NFκB p65 (27.Ser 536): sc-136548的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 p-NFκB p65 Antibody (27.Ser 536) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供p-NFκB p65 Antibody (27.Ser 536) (见下方订购信息).
查看产品引用文献(147) Proteins encoded by the v-Rel viral oncogene and its cellular homolog, c-Rel, are members of a family of transcription factors that include the two subunits of the transcription factor NFκB (p50 and p65) and the Drosophila maternal morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is activated and NFκB is subsequently transported from the cytoplasm to the nucleus in cells exposed to mitogens or growth factors. cDNAs encoding precursors for two distinct proteins have been described, designated p105 and p100. The p105 precursor contains p50 at its N-terminus and a C-terminal region that when expressed as a separate molecule, designated pdI, binds to p50 and regulates its activity.The NFκB transcription factor is a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit, also referred to as Rel A, is functionally related to c-Rel p75 and RelB p68. NFκB p65 is phosphorylated at Serine-311 as a response to protein kinase C ζ.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® an

克隆类别
Replacement monoclonal antibody for: sc-33020, sc-101752.

组成成分
核转录因子抗体、1.0ml磷酸缓冲盐溶液(含0.1%叠氮化钠和0.1%明胶)

数据库链接
Entrez-Gene ID
5970;19697

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