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ERp72 (C-7)

产品介绍
产品信息
宿主
mouse

简单描述
ERp72抗体(C-7)是小鼠单克隆IgG2a κ, 在1篇文献中引用,规格为200 µg/ml免疫原氨基酸序列257-528位于human物种的ERp72的内部区域内推荐用于 mouse, rat 和 human 来源的ERp72 WB, IP, IF, IHC(P) 和 ELISA检测m-IgG Fc BP-HRP 是 ERp72 Antibody (C-7) for WB and IHC(P) 的首选应用二抗。这个产品以套装形式提供 ERp72 Antibody (C-7) (参照下方订购信息).
查看产品引用文献(1) Mammals defend themselves against intracellular pathogens through presentation of cytoplasmically derived short pathogenic peptides to the cell surface of cytotoxic T lymphocytes, which subsequently leads to cytotoxic events with respect to the affected cell. Antigen presentation is mediated by major histocompatibility complex (MHC) class I molecules, which bind and coordinate short pathogenic peptides. The proper folding and assembly of MHC class I molecules in the endoplasmic reticulum (ER) involve a number of components. MHC class I molecules assemble in the ER with chaperones before binding to the transporter associated with antigen processing (TAP) protein. ERp57 is a component of the MHC class I pathway that appears to interact with MHC class I molecules before they associate with TAP. ERp72, also designated protein disulfide-isomerase A4, is involved in the catalysis of protein -S-S- bond rearrangement. ERp57 and ERp72 may act as proteases, protein disulfide isomerases, phospholipases or a combination of these.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-32231, sc-292586.

基因

应用
反应种属
human

数据库链接
Entrez-Gene ID
9601;12304

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