Prostaglandin E2 (10 mg)

5280360

Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

352.47

(5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1oic acid

Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP₁, EP₂, EP₃ and EP₄ receptors (K_d values range between ~ 1 - 10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis.

≥98% (HPLC)

Soluble to 100 mM in DMSO and to 45 mM in ethanol

PGE₂

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

C₂₀H₃₂O₅

363-24-6